Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine. Found insideRevising the manual has been a team exercise. There are contributions from a large number of experts, organizations and institutions. This new edition has seven modules. This is the first book to present vaccine evaluation in this comprehensive conceptual framework. This book is intended for colleagues and students in statistics, biostatistics, epidemiology, and infectious diseases. Smart Health Choices provides the tools for assessing health advice, whether it comes from a specialist, a general practitioner, a naturopath, the media, the internet of a friend. Found insidePraise for the first edition: "Given the author’s years of experience as a statistician and as a founder of the first DMC in pharmaceutical industry trials, I highly recommend this book—not only for experts because of its cogent and ... Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, ... Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics. Found insideThe aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of ... In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. .Fascinating, erudite and beautifully written."—The New York Times Book Review In this groundbreaking work, Kwame Anthony Appiah, hailed as "one of the most relevant philosophers today" (New York Times Book Review), changes the way we ... Integrating Clinical Research into Epidemic Response: The Ebola Experience assesses the value of the clinical trials held during the 2014â€"2015 epidemic and makes recommendations about how the conduct of trials could be improved in the ... The book recommends changes to the Advisory Committee on Immunization Practices (ACIP)-the entity that currently recommends vaccines-and calls for a series of public meetings, a post-implementation evaluation study, and development of a ... Found insideThe text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Found insideBuilding on his earlier work on Attlee and including new research and stories, many of which are published here for the first time, Francis Beckett highlights Attlee’s relevance for a new generation. The book is a useful primer for anyone working to advance the pharmacological management of disease. Found insideA New York Times Bestseller Finalist for the Royal Society Insight Investment Science Book Prize Longlisted for the Wellcome Book Prize This text aims to be a one-stop source for guidance and checking the rules for proper conduct of clinical trials, as well as providing a historical perspective of the clinical research landscape. The classic, definitive guide to the design, conduct, and analysis of randomized clinical trials. As the New England Journal of Medicine notes, “it is critical that those engaged in drug development, clinical research and its oversight, research ethics, and policy know about these stories,” which tell of an impossible choice being ... In Hormones, Health, and Happiness, Dr. Steven Hotze reveals how restoring hormones to optimal levels using natural, bioidentical hormones enables women and men to regain their vitality. This new second edition covers the most current information on DMC policies, issues in monitoring trials using new designs, and recent trial publications relevant to DMC decision-making. • Presents practical advice for those managing and ... Recognizing that clinical trial design is one of the most important and useful skills in the pharmaceutical industry, this book provides detailed discussions on a variety of statistical designs, their properties, and operating ... These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. According to Matthew Yglesias, one billion. From one of our foremost policy writers, One Billion Americans is the provocative yet logical argument that if we aren’t moving forward, we’re losing. This book also explores EBM methodology and its relationship with other approaches used in medicine. This book offers an overview of the statistical methods used in clinical and observational vaccine studies. From HIV to Avian Flu, this is a harrowing look at the dangers we face in a global society, and the ways that we can protect ourselves in the future. Found insideA history of the 1950s polio epidemic that caused panic in the United States examines the competition between Salk and Sabin to find the first vaccine and its implications for such issues as government testing of new drugs and manufacturers ... Found insideCould the secrets to personal health lie within our own brains? Journalist Erik Vance explores the surprising ways our expectations and beliefs influence our bodily responses to pain, disease, and everyday events. Found insideThis book will transform the way we think about who—and what—“we” are. Understanding the story of what happened in those years can help readers make sense of everything taking place across the region today – from the terrorist attacks in North Sinai to the bedlam in Syria and Libya. This collection of intriguing essays describes important applications of statistics and probability in many fields. Instead of teaching methods, the essays illustrate past accomplishments and current uses of statistics and probability. Found insideThis practical guide will be essential reading for postgraduate students in infectious disease epidemiology, health protection trainees, and practicing epidemiologists. Beginning with a review of the role of placebos in the history of medicine, this book investigates the current surge of interest in placebos, and probes the methodological difficulties of saying scientifically just what placebos can and ... Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, that has led many pharmaceutical companies to abandon vaccine manufacture. This book focuses on the remarkable progress in developing vaccines, the amazing effectiveness of the early vaccines, and the challenges of delivering them to the population. Found insideFinalist for the Pulitzer Prize in General Nonfiction A New York Times Bestseller Longlisted for the Andrew Carnegie Medal for Excellence in Nonfiction Winner of the WSU AOS Bonner Book Award As revelatory as Atul Gawande's Being Mortal, ... Choose to take part in this comprehensive conceptual framework to take part in this are! 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