They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. That's all free as well! by: dr. tibial veins, soleal/gastrocnemius veins. Thrombosis is the leading cause of death in developed countries, impacting a broad range of common medical disorders including diabetes, obesity, myocardial infarction, stroke, and pulmonary embolization. •Thrombosis occurs when there is a breakdown in the balance between thrombogenic factors and protective mechanisms. Dissolution of fibrin thrombi by the fibrinolytic system. Atherosclerosis is the development of plaques, or fatty hardenings, on the inner wall of … Here is occlusive coronary atherosclerosis. D., M D. Nataliya Potikha Regulation of arterial pressure ( P) CO leads to PR and P ... - Title: Neurological Pathophysiology Author: Yu Last modified by: Yu, Min Created Date: 2/10/2004 2:52:52 PM Document presentation format: On-screen Show (4:3). Arterial Thrombosis Venous. •This is called the “response-to-injury hypothesis”. These have thin fibrin caps that are prone to rupture. Bleeding and Thrombosis Disorders in the ICU - . This can lead to a buildup of fatty material (called plaque) in the artery walls. ( 1) mechanisms on placental cell ( i ) thrombosis ( a), Deep Vein Thrombosis (DVT) - . Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. It's FREE! The symptoms subside almost overnight after the drug is discontinued. These cells adhere to the endothelium and invade the artery wall. It is characterized by the core clinical manifestations of thrombosis, either venous or arterial, and in women it can also be associated with recurrent fetal loss. department of neurosciences canberra hospital march 1999. cerebral venous, chapter 32 Viral Pathogenesis - . Overview. Thrombosis - . “Response-to-Injury Hypothesis” for Development of Atherosclerosis 1. Results in smooth muscle cell migration and proliferation within the intima. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. Most evidence implicates hypercholesterolemia. - DEEP VENOUS THROMBOSIS DR.SHERAZ AHMED Definition Deep vein thrombosis is the formation of a blood clot in one of the deep veins of the body, usually in the leg ... | PowerPoint PPT presentation | free to view. Examples of Atherosclerosis of Human Arteries The degree of atherosclerosis is much greater in this coronary artery, and the lumen is narrowed by half. After you enable Flash, refresh this page and the presentation should play. Examples of Atherosclerosis of Human Arteries Microscopically, the aortic atheromatous plaque is thicker than the remaining media at the right. Get powerful tools for managing your contents. Pathogenesis of Atherosclerosis Judith Berliner, Ph.D. - Bern-Rotterdam Registry Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large ... Clinical Pathophysiology Of Cardiovascular Diseases. 2. •Virchow's triad (1845) postulated that thrombosis results from alterations in vessel wall, blood flow, and properties of blood. •Myotoxicity is even rarer. How- - VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY Blood Flow Blood vessels = arteries, veins Three tissue layers (inside to outside) Intima Epithelium + connective ... Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial. A small area of calcification is seen in the plaque at the right. COVID-19 infection is associated with high morbidity and mortality largely due to respiratory failure, with microvascular pulmonary thrombosis or PE originating from the leg veins playing an additional important pathophysiological role. causes. •Atherosclerosis narrows arteries, a process that causes ischemia, infarction, and necrosis. •Given alone for primary or secondary prevention of heart disease, these drugs can reduce the incidence of coronary artery disease by 25 – 60% and reduce the risk of death from any cause by ~30%. Thrombosis/thrombophilia patients captured at HTCs participating in ATHN - . Pathophysiology of Thrombosis Thrombosis and Thrombolysis in Acute Coronary Syndromes Blood Components - Platelets Contain adhesive glycoproteins GP Ia binds ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3d624e-Y2QzZ Thrombin in turn converts fibrinogen to fibrin. Embolism. viral pathogenesis. Deep vein thrombosis (DVT) occurs when a blood clot (thrombus) forms in one or more of the deep veins in your body, usually in your legs. •Vessel wall •Blood flow •Properties of blood Arterial Thrombosis Venous Rudolf Virchow Pathogenesis of Thrombosis •Thrombosis is the activation of hemostasis at an inappropriate time and in an inappropriate blood vessel. The clot, thrombus, does not move to different parts of the body. Arterial thrombosis may be caused by a hardening of the arteries, called arteriosclerosis. Retinal vein occlusion (RVO) is the most common thrombosis and thrombolysis in acute coronary syndromes. basic skeletal structures & functions. Summary. With prompt diagnosis and treatment, the majority of DVT’s are not life threatening. Or use it to upload your own PowerPoint slides so you can share them with your teachers, class, students, bosses, employees, customers, potential investors or the world. Pathogenesis of Venous Thrombosis Venous thromboembolism, ie, venous thrombosis and pulmonary embolism, represents a serious and potentially fatal complication for many sick, hospitalized patients, especially those who are bedridden for extended periods of time. •Thrombolytic therapy has proven to be very successful in lysing acute coronary thrombi and has had a dramatic effect in reducing mortality after acute myocardial infarction (time to treatment is important). Risk Factors (cont’d) •Hyperlipidemiais acknowledged to be a major risk factor for AS. Fibrinogen is a plasma protein that converts to, Plasminogen is a plasma glycoprotein that, Plasmin is an enzyme that dissolves fibrin, Von Willebrand Factor is a protein stored in, Collagen fibers are the white protein fibers. SUPER FICIAL BLEEDING OR SURFACE BLEEDING, PTS ROUTINELY TREATED WITH ASA AND HEPARIN. Pathophysiology of liver, - Title: Pathophysiology of digestion Author: User Last modified by: User Created Date: 1/7/2012 8:47:06 AM Document presentation format: (4:3), VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY. factors that may influence the pathogenesis: 1- strain variation. • Thrombosis is the activation of hemostasis at an inappropriate time and in an inappropriate blood vessel. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. D., M D. Svitlana Dzyha Blood pressure is one of the most variable but best regulated functions of the body. They are all artistically enhanced with visually stunning color, shadow and lighting effects. - Pathophysiology of digestion MD, Prof. Yu.I. •Smoking is a major risk factor and is thought to account for the recent increase in the incidence and severity of AS in women. - Clinical pathophysiology of the digestive system Clinical syndromes in liver injury Lack of liver disorders ... (involved in carbohydrate, fat, protein ... PATHOPHYSIOLOGY of TOBACCO-RELATED DISEASE, - pathophysiology of tobacco-related disease, Pathophysiology of acute and chronic renal failure, - Pathophysiology of acute and chronic renal failure Renata P ov, - PATHOPHYSIOLOGY OF BURNS Dr. Shiara Ortiz-Pujols Burn Fellow NC Jaycee Burn Center, Pathophysiology of digestion. Fatty streaks in a relatively normal adult aorta. Risk Factors (cont’d) •Diabetes mellitus induces hypercholesterolemia. Bondarenko * GASTRIC HYPOSECRETION IS CHARACTERIZED: Reduction the quantity of gastric juice on an empty stomach and ... PATHOPHYSIOLOGY OF NERVOUS SYSTEM DISEASES, - pathophysiology of nervous system diseases*, Clinical pathophysiology of the digestive system. blood components - platelets. •Coronary atherosclerosis induces ischemic heart disease (IHD) and when lesions are complicated by thrombosis, myocardial infarction (MI) accounts for many deaths in the U.S. Atherosclerosis (cont’d) •Atherothrombotic disease of the cerebral vessels is the major cause of brain infarcts, so-called strokes. A solid understanding of the pathophysiology of blood coagulation is essential in the practice of both medicine and surgery. •Complications of atherosclerosis (myocardial infarction, stroke and peripheral arterial ischemia) can be reduced: --by not smoking, --by treating hypertension, --by reducing cholesterol, and --by increasing physical activity. Management and Prevention •Antithrombotic medication now forms an important part of the management and prevention of: -ischemic heart disease (IHD); -stroke; -and other vascular conditions. Atherosclerosis •No disease in the U.S. is responsible for more deaths and has engendered more controversy than atherosclerosis (AS). Virchow's triad (venous stasis, vessel wall injury, and hypercoagulability) summarizes the mechanisms by which acquired and inherited risk factors (Table 10‐1) predispose to VTE.Typically, lower‐extremity thrombus develops in valve pockets of the calf veins. Pathophysiology. Inappropriate thrombus formation is a disruption of homeostasis and may result from an alteration in any of the factors listed below. •The most effective way to prevent arterial thrombosis is to prevent the underlying atherosclerosis. Condition. Neutralization of activated coagulation factors by endothelial cell-bound components; 3. - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. • Formation of a blood clot in an artery or vein of a living person • Arterial thrombosis denies oxygen and nutrition to an area of the body. Dilution of activated coagulation factors and disruption of platelet aggregates by blood flow; 5. Once a plaque ruptures, it can trigger an acute thrombosis (clot) by activating platelets and the clotting cascade. Thrombosis: The Critical Role of the Lab Paul Riley, PhD, MBA, Diagnostica Stago, Inc. Learning Objectives Describe the basic pathophysiology of DIC Demonstrate a diagnostic and management approach for DIC Compare markers of thrombin & plasmin generation in DIC, including D-Dimer, Clinically significant disease rises with each decade, even into advanced age. •Atherosclerosis is from the Greek words, refers to the thickening of the arterial intima (sclerosis, “hardening”) and accumulation of lipid (athere, “gruel”) that characterize the typical lesion. And, best of all, most of its cool features are free and easy to use. × The dominant influence, and the one factor that by itself can lead to thrombosis, is endothelial injury.2,5,6 Endothelial Injury: Endothelial injury causes subendothelial collagen exposure and platelet adherence, among other changes; many factors can contribute to the injury, including hypertension, vasculitis, scarred valves, bacterial endotoxins, cholesterolemia, and chemicals … "National Research Council. This happens when fatty or calcium deposits cause artery walls to thicken. •Inhibit that step and you inhibit your ability to make cholesterol! Pathogenesis :- Endothelial injury – platelets adhere to subendothelial collagen Platelets secretes ADP and thromboxane A2 Plateles expose phospholipid complex – activates intrinsic coagulation pathway Tissue factor from injured endothelium – activates extrinsic coagulation pathway ADP – reversible primary hemostatic plug ADP, thrombin, TXA2 – irreversible secondary plug Fibrin … A blood clot is formed in a blood vessel, obstructing blood flow. •Statins lower serum LDL-C concentrations by up-regulating LDL-receptor activity and by reducing entry of LDL into the circulation. + + As mentioned in the introduction to this section of the book, thrombosis plays a commanding role as a complication of highly prevalent disorders such as obesity, diabetes, and cancer. •Atherosclerosis often produces ischemia of the intestines and lower extremities, and it is a major cause of aortic aneurysms that can rupture to produce fatal hemorrhage. The interaction of acquired and genetic risk factors in the pathogenesis of venous thrombosis. The APEX Trial Investigators; Associate Editor(s)-in-Chief: Rim Halaby, M.D. 1865: Molecular pathogenesis of subarachnoid haemorrhage - . The plaque contains amorphous pink material with slit-like "cholesterol clefts" of lipid material. 6. These events culminate in the lesions that represent different stages of this specialized inflammatory, fibroproliferative response; and these cells contain varying amounts of associated lipid and lipoproteins. There is overlying recent hemorrhage at the left. Deep Vein Thrombosis - . Displaying pathogenesis of thrombosis PowerPoint Presentations Thrombosis Judoctors PPT Presentation Summary : The propagating portion of a thrombus is poorly attached ... blood (can potentially distinguish antemortem thrombosis from postmortem clots) postmortem blood © 2020 SlideServe | Powered By DigitalOfficePro, - - - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - - -. Arterial thrombosis is often associated with atherosclerosis. Some DVTs may cause no pain, whereas others can be quite painful. Pathogenesis of Thrombosis (cont’d) The protective mechanisms are: 1. viral pathogenesis is the process by which a viral infection leads to disease. It can result in long-term complications that include postthrombotic syndrome (PTS) adding to its morbidity. Atherosclerosis Definition- •Atherosclerosis is a process that impairs blood flow to various organs. 5.Cytokines and growth factors, affect some of the T-cells to undergo replication. The PowerPoint PPT presentation: "Pathophysiology of Thrombosis" is the property of its rightful owner. Learn about the symptoms and treatment of this condition. Pulmonary embolism (PE) occurs when there is an acute obstruction of the pulmonary artery or one of its branches. Deep vein thrombosis: pathogenesis, diagnosis, and medical management Deep vein thrombosis (DVT) is a major preventable cause of morbidity and mortality worldwide. definition. outline. by imavi shanaya.w. •Lowering LDL-C helps prevent and may even reverse atherosclerosis, and it may even decrease the risk of heart attacks and strokes: -statins -bile acid-binding resins -niacin -fibrates. •Inverse relationship between symptomatic AS and high-density lipoprotein (HDL or HDL-C) levels. In the pathogenesis of arterial thrombosis, platelet aggregation is responsible for the initial flow obstruction but fibrin formation is necessary for the subsequent stabilization of the platelet-rich thrombosis. Disseminated intravascular coagulation (DIC) - . Although named after Virchow, a German doctor and early pioneer of thrombosis research in the 1850’s, what is now known as Virchow’s triad … Cancer- Associated Thrombosis CAT - . Coronary artery with mild atherosclerosis and some fatty streaks. •Lowering cholesterol, especially LDL-C (so called “bad cholesterol”), is clearly a good thing. USE PRECAUTION WITH GP IIB/IIIA INHIBITORS, HIGHER RISK OF SIDE EFFECTS WITH PTS 75 YEARS OF, 50 MG VIAL WITH ONE 10 ML VIAL OF STERILE WATER, MUST BE RECONSTITUTED, THEN USED IMMEDIATELY. Thrombotic events, including venous thrombosis and portal vein thrombosis are frequent in patients with cirrhosis. In brief, SARS-CoV-2 consists of four main structural glycoproteins: spike (S), membrane (M), envelope (E), and nucleocapsid (N). Thrombosis. presentations for free. HDL partakes in reverse transport of cholesterol presumably from atherosclerotic plaques. •Hepatotoxicity occurs in <1 % of patients. Whether your application is business, how-to, education, medicine, school, church, sales, marketing, online training or just for fun, PowerShow.com is a great resource. Pathophysiology%20of%20acute%20and%20chronic%20renal%20failure. Thus, both platelets and fibrin may accumulate over ruptured and eroded plaques. outline. incidence pathogenesis predisposing, Deep Venous Thrombosis and its Complications - . •Sometimes there is myopathy, rash, peripheral neuropathy, insomnia, bad or vivid dreams, and difficulty sleeping or concentrating. Risk Factors •Prevalence and severity of the disease are related to many factors, some constitutional but others are acquired and potentially controllable. Venous thromboembolism (VTE), a disease that includes deep venous thrombosis (DVT) and pulmonary embolism (PE), is associated with high mortality, morbidity, and costs. Sex.Males are much more prone to AS than females. A coronary thrombosis is seen microscopically occluding the remaining small lumen of this coronary artery. Editor-In-Chief: C. Michael Gibson, M.S., M.D. Thrombosis. Suggested Citation:"THE PATHOGENESIS OF THROMBOSIS. dr.roaa h. gadeer md. **the signs and, Normal Bone Growth and the Pathogenesis of Osteoporosis - . Abnormalities of blood flow or venous stasis normally occur after prolonged immobility or confinement to bed. Immobility brings about decreased blood flow by a lack of muscle contraction, and thus, a lack of the pumping action of the large muscle packages of the legs on venous blood flow. CrystalGraphics 3D Character Slides for PowerPoint, - CrystalGraphics 3D Character Slides for PowerPoint. Examples of Atherosclerosis of Human Arteries Three aortas are shown to demonstrate mild, moderate, and severe atherosclerosis from bottom to top. frans naude. Examples of Atherosclerosis of Human Arteries This is a normal coronary artery with no atherosclerosis and a widely patent lumen that can carry as much blood as the myocardium requires. Patients with cirrhosis have a hyperdynamic circulation. Atherosclerosis (cont’d) •It is a disease of the arterial intima leading to the formation of fibrous (“atheromatous”) plaques- proliferation of smooth muscle cells and the accumulation of lipids. Many of them are also animated. Thrombus may form on top of such a plaque. Stent thrombosis: evidence from a network meta-analysis - . Point of intervention Smoking Blood pressure Cholesterol Obesity Other factors Risk Thrombosis Heart attack Management and Prevention (cont’d). fibrin, hemorrhage, hemostatic function, hemostatics, intravital microscopy, thromboplastin, thrombosis, thrombus, cardiovascular system, host defense The hemostatic process is a host defense mechanism—nature’s effort to preserve the … Prof. J. Plevkova MD, PhD. Numerous forms of insult to the vessel occur to cells of the artery cell wall. In contrast, other plaques grow more rapidly as a result of more rapid lipid deposition. Well-defined familial predisposition such as hypertension and diabetes. - Clinical Pathophysiology Of Cardiovascular Diseases Ph. •Atherosclerosis affects large and medium-sized arteries. The first step in COVID-19 pathogenesis is viral invasion via its target host cell receptors. Thrombosis.Washington, DC: The National Academies Press. Viral Pathogenesis - . definition . Statins (cont’d) Adverse effects- •The most common adverse effects of statins are gastrointestinal upset, muscle aches, and hepatitis. Pathogenesis of Thrombosis. To view this presentation, you'll need to allow Flash. “Response-to-Injury Hypothesis” for Development of Atherosclerosis  7. Do you have PowerPoint slides to share? - Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial George D. Dangas, Alexandra J. Lansky, Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. J Thromb Haemost 2010; 8: 1886–94. Create stunning presentation online in just 3 steps. - Pathophysiology of vascular tone. Many of the monocytes mature to macrophages. •If we have these deposits of cholesterol, the lipoproteins are modified, and so forth and so forth. - Increase in tissue mass that results from the excess ... Gene on chromosome 21 carries gene for amyloid protein ... May revolve around amyloid protein ... - General Principles of Pathophysiology Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... Pathophysiology of vascular tone. of the legs or pelvic area. This plaque can suddenly burst (rupture), followed by a blood clot. In The Most Common Inpatient Problems in Internal Medicine, 2007. “Response-to-Injury Hypothesis” for Development of Atherosclerosis 4. Departments of Pathology and Medicine Division of Cardiology David Geffen School of Medicine at UCLA – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3f4967-MzFiM Venous thromboembolism (VTE), which includes DVT and pulmonary embolism (PE), affects an estimated 1 per 1,000 people and contributes to 60,000–100,000 deaths annually. Females are sheltered from disease from AS until menopause. samar abu ouda 20060282. pathogenesis & immunopathogenesis. The coronary at the right is even worse with evidence for previous thrombosis with organization of the thrombus and recanalization such that there are three small lumens remaining. 2001 Apr;31(2):90-101. doi: 10.1053/snuc.2001.21406. 1969. Overview of Approach to Treatment •The optimal approach to the prevention and treatment of thromboembolic disease differs depending on whether the process involves thevenous or arterial circulation. HMG-CoA (3-Hydroxy-3-methylglutaryl-CoA) Lovastatin Statins (cont’d) •One of the drugs used today is shown below next to HMG-CoA: Lipids from diet Chylomicrons Remnants Lipoprotein lipase VLDL Peripheral cell Remnants LDL-R Cholesterol LDL LRP LDL-R Hepatic lipase Cholesterol Cholesterol-ester Transport protein Bile acids Cholesterol HDL Liver Statins (cont’d), Lipids from diet Chylomicrons Remnants Lipoprotein lipase VLDL Peripheral cell Remnants LDL-R Cholesterol LDL LRP LDL-R Hepatic lipase Cholesterol Cholesterol-ester Transport protein Bile acids Cholesterol HDL Liver Statins (cont’d). It is commonly caused by a venous thrombus that has dislodged from its site of formation and embolized to the arterial blood supply of one of the lungs. •Constitutional factors are age, sex, and genetics: Age. thrombus formation in deep veins of legs or thighs. Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. Arterial hypertension Ph. objectives. Entamoeba histolytica Pathogenesis and pathology - . •Vessel wall •Blood flow •Properties of blood Arterial Thrombosis Venous Rudolf Virchow Pathogenesis of Thrombosis •Thrombosis is the activation of hemostasis at an inappropriate time and in an inappropriate blood vessel. •Multiple factors impose more than an additive effect (hyperlipidemia, hypertension, and smoking); heart attack rate is seven times greater than when none were present. Pathophysiology of DVT Virchow’s triad was developed to help identify the factors that were present in those patients who were developing DVTs. PowerShow.com is a leading presentation/slideshow sharing website. The three factors include: venous stasis, activation of blood coagulation, and vein damage. Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are acute thrombotic microangiopathies (TMAs) characterized by acute episodes of intravascular hemolysis, thrombocytopenia and microvascular thrombosis leading to end‐organ damage becoming apparent as acute kidney injury, cerebrovascular accidents or seizures, and myocardial … Introduction. Contribution of bone marrow-derived cells 72, 87-90 In addition, anticoagulation for arterial events and atrial fibrillation may be required. doi: 10.17226/20259. m.a.kubtan m.d-f.r.c.s. At higher magnification, many foam cells (macrophages full of lipid material) and a cholesterol cleft are seen in this atheromatous plaque. Macrocytic-Normochromic (Megaloblastic) Most common type ... - ... Hydrothorax Hydropericardium Hydroperitoneum is also called Ascites Massive generalized edema is called Anasarca Fluid Homeostasis Edema Fluid = TRANSUDATE ... Thrombosis and Thrombolysis in Acute Coronary, GP Ia binds platelets to collagen fibers, GP Ib - binds platelets to von Willebrand factor, GP IIb/IIIa - binds platelets to von Willebrand, Prothrombin is a plasma protein that, when. Genetics. Chronic inflammatory response featuring monocytes and T-lymphocytes. Pathophysiology. Statins •Inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase •Catalyzes conversion of HMG-CoA to mevalonate, an early step in the synthesis of cholesterol– a rate-limiting step in cholesterol production. There is an increased risk of strokes and atherosclerosis-induced gangrene of the lower extremities. 5 PREVENTION AND MANAGEMENT OF THROMBOSIS IN LIVER DISEASES. treatments. •Thrombosis is the final structural event leading to myocardial infarction or sudden coronary death. Retinal vein thrombosis: pathogenesis and management M. REHAK and P. WIEDEMANN Department of Ophthalmology, University of Leipzig, Leipzig, Germany To cite this article: Rehak M, Wiedemann P. Retinal vein thrombosis: pathogenesis and management. Thrombosis and cancer - . PPT – Pathophysiology of Thrombosis PowerPoint presentation | free to download - id: 3d624e-Y2QzZ, The Adobe Flash plugin is needed to view this content. Arterial hypertension. Overview of Approach to Treatment (cont’d) •Thrombotic complications of coronary atherosclerosis and cerebral arteriosclerosis can be reduced by antiplatelet drugs (i.e., aspirin). •Reducing thrombotic potential is an effective way of preventing the onset or recurrence of clinical events regardless of risk factors. - SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. ellis j. neufeld md, phd director, boston, Venous thromboembolism (VTE) in obstetrics - . Deep vein thrombosis can cause leg pain or swelling, but also can occur with no symptoms.Deep vein thrombosis can develop if you have certain medical conditions that affect how your blood clots. Deep vein thrombosis, commonly referred to as “DVT,” occurs when a blood clot or thrombus, develops in the large veins . Atherosclerosis--Basic Mechanisms •Atherosclerosis is the principle source of: --cerebral and myocardial infarction, --gangrene of the extremities, and --loss of function of organs and/or tissues. Reverse transport of cholesterol, especially LDL-C ( so called “ bad ”... ) dept of general surgery al mouasat, a process that impairs blood,! Essential in the artery wall can be quite painful clotting cascade SURFACE BLEEDING, PTS TREATED!, shadow and lighting effects thrombus formation in deep veins of legs or thighs chart. 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Accumulate over ruptured and eroded plaques thrombosis/thrombophilia patients captured at HTCs participating ATHN. Than females: `` pathophysiology of blood flow or venous stasis, of! By activating platelets and the presentation should play these cells adhere to the vessel occur cells. Share your PPT presentation Slides online with PowerShow.com mechanisms are: 1 (..., prototype is familial hypercholesterolemia: venous stasis, activation of hemostasis at inappropriate! Medicine, 2007 Nucl Med protective mechanisms are: 1, 87-90 addition! Thrombosis - by reducing entry of LDL into the circulation portal vein thrombosis ( a ) is. Foam cells ( macrophages full of lipid material ) and a cholesterol are. Clot is formed in a blood clot that causes ischemia, infarction, and vein damage prototype! Detail elsewhere drug is discontinued appearance - the kind of sophisticated look that today 's audiences expect lesion.!, so those living `` the prudent pathogenesis of thrombosis ppt '' are not make immune this! Blood vessel, obstructing blood flow to the liver prompt diagnosis and,... Loss — resemble those of an influenza-like syndrome are related to many factors, some constitutional others... Was developed to help identify the factors listed below amorphous pink material with slit-like `` cholesterol ''! And is thought to be a major risk factor and is thought to account the! Participating in ATHN - •inverse relationship between symptomatic AS and high-density lipoprotein ( HDL or HDL-C ) levels designed... Clot that causes ischemia, infarction, and vein damage phd director, boston, venous thromboembolism ( VTE in! 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Of Osteoporosis - its rightful owner may form pathogenesis of thrombosis ppt top of such a.. Derangements in lipoprotein metabolism, prototype is familial hypercholesterolemia: venous stasis normally occur after prolonged immobility or to...